Gene expression profile of renal cell carcinoma clear cell type
نویسندگان
چکیده
منابع مشابه
Gene expression profile of renal cell carcinoma clear cell type.
PURPOSE The determination of prognosis in patients with renal cell carcinoma (RCC) is based, classically, on stage and histopathological aspects. The metastatic disease develops in one third of patients after surgery, even in localized tumors. There are few options for treating those patients, and even the new target designed drugs have shown low rates of success in controlling disease progress...
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BACKGROUND Acidic extracellular pH is a major feature of tumor tissue. Acid-sensing ion channels (ASICs) represent an H(+)-gated subgroup of the degenerin/epithelial Na(+) channel family and are activated by acidic microenvironment. Little is known about the expression and clinical significance of ASICs in solid tumors. The purpose of this study was to examine the expression of ASIC1 in human c...
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ژورنال
عنوان ژورنال: International braz j urol
سال: 2010
ISSN: 1677-5538
DOI: 10.1590/s1677-55382010000400004